PTEN Deletion (39781bp Del with Exon 2-3 Del) Reference Standard
CBP10699
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產品描述
產品數(shù)據(jù)庫
| Introduction | |
| Gene | PTEN |
| Description | PTEN, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, is a tumor suppressor with roles in the cell cycle, growth, DNA repair, cell survival and regulation of the Akt-mTOR pathway. PTEN germline mutations are common in Cowden syndrome and PTEN somatic alterations resulting in loss of function have been found in many types of cancer including, but not limited to endometrial, melanoma, and prostate. |
| Technical Data | |
| Left Breakpoint | chr10-89646816 |
| Right Breakpoint | chr10-89686598 |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
